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Analgesic Efficacy of Subcutaneous�Oral Dosage of Tramadol after Surgery in C57BL/6J Mice
Analgesic Efficacy of Subcutaneous�Oral Dosage of Tramadol after Surgery in C57BL/6J Mice
This study investigated the analgesic activity of tramadol in female C57BL/6J mice by using a single subcutaneous injection (25 mg/kg) of tramadol combined with the same dose given in drinking water for 24 h. We then evaluated the pharmacokinetics of t...
An Efficient, Simple, and Noninvasive Procedure for Genotyping Aquatic and Nonaquatic Laboratory ...
An Efficient, Simple, and Noninvasive Procedure for Genotyping Aquatic and Nonaquatic Laboratory ...
Various animal models are indispensible in biomedical research. Increasing awareness and regulations have prompted the adaptation of more humane approaches in the use of laboratory animals. With the development of easier and faster methodologies to gen...
Methods for Investigating the Motivation of Mice to Explore and Access Food Rewards
Methods for Investigating the Motivation of Mice to Explore and Access Food Rewards
The emotional state of domestic animals is an essential component of the assessment of their welfare. In addition, sensitivity to various rewards can be a valuable indicator when investigating these states.
Minimum Alveolar Concentration and Cardiopulmonary Effects of Isoflurane in Ring-tailed Lemurs (L...
Minimum Alveolar Concentration and Cardiopulmonary Effects of Isoflurane in Ring-tailed Lemurs (L...
The goal of this study was to determine the minimum alveolar concentration (MAC) and cardiopulmonary effects of isoflurane in ring-tailed lemurs (Lemur catta).
Effects of Time and Storage Conditions on the Chemical and Microbiologic Stability of Diluted Bup...
Effects of Time and Storage Conditions on the Chemical and Microbiologic Stability of Diluted Bup...
Buprenorphine is a partial ?-opioid agonist used for analgesia. Due to the small size of laboratory rodents, buprenorphine HCl is typically diluted 10- or 20-fold with a sterile diluent, such as saline, for accurate dosing. Protocols for preparing and ...
Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice
Effect of Early-life Gut Mucosal Compromise on Disease Progression in NOD Mice
Disease expression in spontaneous nonobese diabetic (NOD) mice depends on environmental stimuli such as stress, diet, and gut microbiota composition.